The Adventures of Sebastian Cole was released in the year 1998。

In June, 1983, in Dutchess County, New York, Sabastian Cole joins his mother, step-father, and sister for dinner. Hank, Sabastian's step-father, drops a bomb: he announces he's changing sexes. Sebastian's sister splits immediately for California, and his mother takes him back to England. Jump ahead eight months, Sebastian is back in New York, knocking on Hank's door. Hank (now Henrietta, although all the surgeries aren't complete) takes Sebastian in and is his rock over the next few months of high school. Sebastian's "adventures" are mostly self-destructive.

The Adventures of Sebastian Cole actors and actresses include Adrian Grenier, Aleksa Palladino, Clark Gregg, Famke Janssen, Gabriel Macht, Levon Helm, Marisol Padilla Sánchez, Marni Lustig, Merritt Wever, Miguel Nájera, Nicole Ari Parker, Rory Cochrane。